Polyserositis Induced by Escherichia coli in Gnotobiotic Swine

Immunocompromise in gnotobiotic pigs induced by verotoxin-producing Escherichia coli (O111:NM).

A verotoxin-producing Escherichia coli serotype O111:NM strain (strain 10049; verotoxin 1 positive) persistently infected experimentally inoculated gnotobiotic pigs, causing attaching-effecting intestinal lesions and chronic diarrhea. Experiments were performed to determine whether persistent infection might be associated with immunocompromise of the host of this organism. Pigs inoculated with ...

Production of Escherichia coli-specific hybridomas by using gnotobiotic mice.

Monoclonal antibodies provide a rapid and specific means of direct detection of microorganisms in water and food samples. However, monoclonal antibodies specific for some bacteria are difficult to obtain; a good example of such a bacterium is Escherichia coli. Gnotobiotic BALB/c mice immunized with whole-cell preparations of heat-treated strains of E. coli and subjected to high-frequency antige...

Intestinal Strangulation in Escherichia coli-Monocontaminated Gnotobiotic Rats.

The natural course of ischemic and hemorrhagic intestinal strangulation in previously germ-free rats individually monocontaminated with one of five separate strains of Escherichia coli was investigated. In addition, the effect of intraintestinal homologous heparinized blood upon the course of ischemic intestinal strangulation in E. coli-monocontaminated rats was studied. It was found that (i) E...

Escherichia coli Isolated from Domestic Animals Pathogenic for Gnotobiotic Piglets.

Three strains of Escherichia coli isolated from infectious processes in a calf, a dog, and a cat were examined for their capacity to produce disease or death, or both, in newborn gnotobiotic piglets. The O groups represented by these particular strains of E. coli were O4: (canine origin), O6: (feline origin), and O39: (bovine origin). All three isolates upon oral administration proved to be pat...

Case Report of Meningoencephalitis in Calves Caused by Escherichia coli